Exploring the Effect of Bioisosteric Replacement of Carboxamide by a Sulfonamide Moiety on N??Glycosidic Torsions and Molecular Assembly: Synthesis and X??ray …
…, B Varghese, D Loganathan
文献索引:Srivastava, Amrita; Varghese, Babu; Loganathan, Duraikkannu Chemistry - A European Journal, 2013 , vol. 19, # 52 p. 17720 - 17732
Abstract N-Glycoprotein linkage region constituents, 2-acetamido-2-deoxy-β-D- glucopyranose (GlcNAc) and asparagine (Asn) are conserved among all the eukaryotes. To gain a better understanding for nature's choice of GlcNAcβAsn as linkage region constituents and inter-and intramolecular carbohydrate–protein interactions, a detailed systemic structural study of the linkage region conformation is essential. Earlier ...