Exploring the Effect of Bioisosteric Replacement of Carboxamide by a Sulfonamide Moiety on N??Glycosidic Torsions and Molecular Assembly: Synthesis and X??ray …

…, B Varghese, D Loganathan

Index: Srivastava, Amrita; Varghese, Babu; Loganathan, Duraikkannu Chemistry - A European Journal, 2013 , vol. 19, # 52 p. 17720 - 17732

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Citation Number: 5

Abstract

Abstract N-Glycoprotein linkage region constituents, 2-acetamido-2-deoxy-β-D- glucopyranose (GlcNAc) and asparagine (Asn) are conserved among all the eukaryotes. To gain a better understanding for nature's choice of GlcNAcβAsn as linkage region constituents and inter-and intramolecular carbohydrate–protein interactions, a detailed systemic structural study of the linkage region conformation is essential. Earlier ...