Modular assembly of purine-like bisphosphonates as inhibitors of HIV-1 reverse transcriptase

CM Lacbay, J Mancuso, YS Lin, N Bennett…

文献索引：Kambe, Satoshi; Saito, Koji; Sakurai, Akio; Midorikawa, Hiroshi Synthesis, 1980 , # 5 p. 366 - 368

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被引用次数: 11

摘要

... transcriptase (RT) inhibitors, a new chemotype of nonhydrolyzable purine diphosphate mimic was synthesized. ... identified analogs of PYPY-BPs that inhibit HIV-1 RT-catalyzed DNA synthesis. ... results were previously reported for the mesoxalic acid derivative 5, which presumably ...