Organic letters

Preparation of polyfunctional zinc organometallics using an Fe-or Co-catalyzed Cl/Zn-exchange

L Melzig, CR Diène, CJ Rohbogner, P Knochel

文献索引：Melzig, Laurin; Diene, Coura R.; Rohbogner, Christoph J.; Knochel, Paul Organic Letters, 2011 , vol. 13, # 12 p. 3174 - 3177

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被引用次数: 8

摘要

A new Fe-or Co-catalyzed Cl/Zn-exchange reaction allows the direct transformation of aryl, heteroaryl, and also alkyl chlorides into the corresponding zinc reagents. The method tolerates functional groups such as a nitrile or an ester. Remarkably, secondary and tertiary alkyl chlorides are suitable substrates for the Cl/Zn exchange.