Silyl-cupration of an acetylene followed by ring-formation

I Fleming, EM de Marigorta

文献索引：Fleming, Ian; De Marigorta, Eduardo Martinez Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 8 p. 889 - 900

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被引用次数: 27

摘要

The acetylenes 1a–e undergo silyl-cupration followed by cyclisation, the acetylenes 1f–1h react with the silyl-cuprate reagent more rapidly at the alternative electrophilic site, and the acetylenes 1i, 1j and 17 give relatively low yields of cyclic products amongst others. Ring- formation is, unusually, a not particularly favourable pathway.