Helvetica chimica acta

Preparation of a Key Intermediate for the Synthesis of the (±)??Pentalenolactone E Methyl Ester by Catalytic 'Palladium??Ene Cyclization'/Methoxycarbonylation

W Oppolzer, JZ Xu, C Stone

文献索引：Oppolzer, Wolfgang; Xu, Jin-Zhu; Stone, Charles Helvetica Chimica Acta, 1991 , vol. 74, # 3 p. 465 - 468

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被引用次数: 40

摘要

Abstract Bicyclic alcohol (±)-2, an advanced intermediate for the synthesis of the methyl ester 1 of pentalenolactone E, has been synthesized in nine operations starting from aldehyde 7. The key step 6 [RIGHTWARDS ARROW] 9 is a Pd-catalyzed, tandem intramolecular alkyne allylation/carbonylation reaction.