Thirty-six halogenated Me Et ethers have been synthesized for evaluation as volatile general anesthetics. Eleveii of the ethers were too unstable t, o test, and, of the remaining 25, 13 had promising anesthetic properties in mice and are suitable for study in larger animals. Those ethers having one H with at least 2 halogens other than F or 2 or more H with at least one Br or one C1 were the best anesthetics.
