Preparation of imidazo [2, 1??b] quinazolin??5 (3H)??ones and related tricyclic systems using a novel, double displacement reaction

NP Peet, J Malecha, ME Letourneau…

文献索引：Peet, Norton P.; Malecha, James; LeTourneau, Michael E.; Sunder, Shyam Journal of Heterocyclic Chemistry, 1989 , vol. 26, p. 257 - 264

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被引用次数: 9

摘要

Abstract New methodology is described for the construction of tricyclic heterocycles. Thus, a double displacement reaction of l-(2-fluorobenzoyl)-2-methylthio-2-imidazoline (8a) with 1, 1- dialkylhydrazines gave 10-substituted 2, 10-dihydroimidazo [2, 1-b] quinazolin-5 (3H)-ones in good yield. The corresponding 1-(2-nitrobenzoyl)-2-meth-ylthio-2-imidazolines also underwent double displacement reactions with hydrazines. Other tricyclics made using ...