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Organic letters

Intramolecular Dehydrative Coupling of Tertiary Amines and Ketones Promoted by KO-t-Bu/DMF: A New Synthesis of Indole Derivatives

W Wei, X Dong, S Nie, Y Chen, X Zhang, M Yan

文献索引:Wei, Wen-Tao; Dong, Xue-Jiao; Nie, Shao-Zhen; Chen, Yan-Yan; Zhang, Xue-Jing; Yan, Ming Organic Letters, 2013 , vol. 15, # 23 p. 6018 - 6021

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被引用次数: 22

摘要

Indole derivatives are abundant in natural products, synthetic drugs, and materials.(1) Their synthetic methods have attracted great attention during the past 100 years.(2, 3) Although a number of successful methods have been developed, new synthetic approaches are still desirable considering the great structural diversity of indole derivatives. In recent years, there has been increasing interest in the direct functionalizations of α C–H bonds of amines.(4) The generation of ...