Exploration of the activity of 7-pyrrolidino-8-methoxyisothiazoloquinolones against methicillin-resistant Staphylococcus aureus (MRSA)

HY Kim, JA Wiles, Q Wang, GCG Pais…

文献索引：Fedij, Victor; Lenoir, Edward A.; Suto, Mark J.; Zeller, James R.; Wemple, James Tetrahedron: Asymmetry, 1994 , vol. 5, # 7 p. 1131 - 1134

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被引用次数: 16

摘要

... Volume: Page: ... Achillion Pharmaceuticals, Inc., 300 George Street, New Haven, Connecticut 06511, United States. J. Med. ... c) 2 (0.9 equiv), N,N-diisopropylethylamine (5 equiv), DMSO, 120 °C, 3 h; (d) preparative HPLC to separate isomers, 20% for 9b(R,S) and ...