Suzuki cross-coupling/reductive debenzyloxycarbonylation sequence for the syntheses of [c] annulated isoquinolines: Application for the syntheses of pancratistatin- …
G Pandey, M Balakrishnan
文献索引:Pandey, Ganesh; Balakrishnan, Madhesan Journal of Organic Chemistry, 2008 , vol. 73, # 20 p. 8128 - 8131
A two-step strategy involving Suzuki cross-coupling of boronic acids with a diverse array of α- iodoenones followed by hydrogenation is developed for the construction of [c] annulated isoquinolines. This mild and efficient procedure is also applied to the synthesis of highly oxygenated isoquinolines.