... to synthesize optically active 3-azabicy- clo[3.3.0]octane-2,6,8-tricarboxylic acid (2). In this paper, we report a synthetic approach to 2 and the related chemistry. ... Faculty of Pharmaceutical Sciences, Hokuriku University; Kanagawa-machi Ho-3, Kanazawa 920–1181, Japan. ... Vol. ...