Molecules

(E)-5-styryl-1H-indole and (E)-6-styrylquinoline derivatives serve as probes for β-amyloid plaques

Y Yang, HM Jia, BL Liu

文献索引：Yang, Yang; Jia, Hong-Mei; Liu, Bo-Li Molecules, 2012 , vol. 17, # 4 p. 4252 - 4265

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被引用次数: 9

摘要

Abstract: We report the synthesis and biological evaluation of novel (E)-5-styryl-1 H-indole and (E)-6-styrylquinoline derivatives as probes for imaging β-amyloid (Aβ) plaques. These derivatives showed binding affinities for Aβ 1–40 aggregates with K i values varying from 4.1