Tetrahedron: Asymmetry

Catalytic asymmetric hydrogenation of α-ketoesters and quinoline using electronically enriched BINAP

…, M Alame, S Pellet-Rostaing, M Lemaire

文献索引：Jahjah, Mohamad; Alame, Mohamad; Pellet-Rostaing, Stephane; Lemaire, Marc Tetrahedron Asymmetry, 2007 , vol. 18, # 19 p. 2305 - 2312

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被引用次数: 39

摘要

Electronically enriched chiral BINAP derivatives were synthesized incorporating electron- donating substituents at the para-phenyl position and evaluated for the Ru-catalyzed homogeneous asymmetric hydrogenation of α-ketoesters with up to 92% ee. These diphophosphines were also excellent ligands for the iridium-catalyzed asymmetric hydrogenation of quinolines.