Heterocyclic Amines with Antihistaminic Activity1

CP Huttrer, C Djerassi, WL Beears…

文献索引：Huttrer et al. Journal of the American Chemical Society, 1946 , vol. 68, p. 1999,2000

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被引用次数: 56

摘要

Extensive work from Fourneau's Laboratory2 has indicated that some relatively simple aminoethers (type F929, F1379, F1464) 3 and diamines: t\-pe Flt5il, FLG91, F1'709, RP 2339, RP 2325) 4 possesset. antihistaniinic activity. Since tertiary amines of this group containing heterocyclic radicals had so far not been studied, we have synthesized a number of asymmetricallysubstituted ethylenediarnines of the general type