Heterocyclic Amines with Antihistaminic Activity1

CP Huttrer, C Djerassi, WL Beears…

Index: Huttrer et al. Journal of the American Chemical Society, 1946 , vol. 68, p. 1999,2000

Full Text: HTML

Citation Number: 56

Abstract

Extensive work from Fourneau's Laboratory2 has indicated that some relatively simple aminoethers (type F929, F1379, F1464) 3 and diamines: t\-pe Flt5il, FLG91, F1'709, RP 2339, RP 2325) 4 possesset. antihistaniinic activity. Since tertiary amines of this group containing heterocyclic radicals had so far not been studied, we have synthesized a number of asymmetricallysubstituted ethylenediarnines of the general type