Tetrahedron letters

One-pot palladium-catalyzed highly chemo-, regio-, and stereoselective synthesis of trans-stilbene derivatives. A concise and convenient synthesis of resveratrol

T Jeffery, B Ferber

文献索引：Jeffery, Tuyet; Ferber, Benoit Tetrahedron Letters, 2003 , vol. 44, # 1 p. 193 - 197

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被引用次数: 68

摘要

A convenient, efficient and highly chemo-, regio-, and stereoselective one-flask synthetic method is reported for the construction of unsymmetrical (or symmetrical) trans-stilbene derivatives based on two sequential Heck-type reactions using tetraalkylammonium salt- based catalyst systems and vinyltrimethylsilane as double bond equivalents. Resveratrol has thus been concisely synthesized.