Silane reductions in acidic media. IV. Reductions of alkyl-substituted cyclohexanones by mono-, di-, and trialkylsilanes. Stereochemistry of alcohol and ether formation
MP Doyle, CT West
文献索引：Doyle,M.P.; West,C.T. Journal of Organic Chemistry, 1975 , vol. 40, # 26 p. 3821 - 3829
Results Reductions in Aqueous Sulfuric Acid-Ethyl Ether Mixtures. Aldehydes and ketones are conveniently reduced to alcohols without structural rearrangement by alkylsilanes in aqueous sulfuric acid using ethyl ether as the solvent. la The alkylsilanes are, in turn, oxidized to the corresponding alkylsilanols. The relative yields of the thermodynamically less stable alcohol from the reductions of selected alkyl-substituted cyclohexanones by mono-, ...
