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The Journal of Organic Chemistry

Thiosugars. I. Synthesis of Derivatives of 2-Amino-2-deoxy-1-thio-D-glucose1

D Horton, ML Wolfrom

文献索引:Horton,D.; Wolfrom,M.L. Journal of Organic Chemistry, 1962 , vol. 27, p. 1794 - 1800

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被引用次数: 120

摘要

The known effectiveness of 8-and y-aminothiol systems in protecting living tissue from damage by ionizing radiation2 suggested that a carbohydrate molecule containing these functional groups might also have radiation protective ability, and at the same time be more physiologically acceptable than noncarbohydrate analogs, most of which are fairly toxic. Derivatives containing the 3-amino-3-deoxy-2-thio-~-al1ose~ and 3-amino-3-deoxy-2-thio ...