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Organic & biomolecular chemistry

Polystyrene-supported TBD catalyzed ring-opening of N-tosylaziridines with silylated nucleophiles

S Matsukawa, T Harada, S Yasuda

文献索引:Matsukawa, Satoru; Harada, Takeru; Yasuda, Shiori Organic and Biomolecular Chemistry, 2012 , vol. 10, # 25 p. 4886 - 4890

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被引用次数: 12

摘要

Aziridines are very useful intermediates for the synthesis of numerous nitrogen-containing biologically active compounds. 1 Therefore, nucleophilic ring-opening of aziridines by various approaches has been widely examined and developed. 2 Among these approaches, the ring-opening reaction using silylated nucleophiles, such as silyl cyanide, azide or halides, is important to produce highly functionalized compounds. Therefore, the catalytic ring-opening reaction with silylated ...