Cinétique et mécanisme de la réaction de knoevenagel dans le benzène-2: Réaction du malonitrile et de la (+) méthyl-3 cyclohexanone en présence d'une amine …
J Guyot, A Kergomard
文献索引：Guyot, J.; Kergomard, A. Tetrahedron, 1983 , vol. 39, # 7 p. 1167 - 1179
The kinetics of the reaction of (+)-3-methyl cyclohexanone with malononitrile were studied in benzene at 25°, in the presence of hexylamine-acetic acid mixtures. Hexylamine gives an imine with cyclohexanone in an acid-catalysed step. This imine then reacts quickly with malononitrile. A rate law of zero order in malononitrile is observed. Separate kinetic results obtained for the formation of the imine and for the imine-malonitrile reaction support this ...
