Synthesis of quinazoline-2, 4-dione and naphthalimide derivatives as new 5-HT3 receptor antagonists

M Langlois, JL Soulier, V Rampillon, C Gallais…

文献索引：Langlois; Soulier; Rampillon; Gallais; Bremont; Shen; Yang; Giudice; Sureau European Journal of Medicinal Chemistry, 1994 , vol. 29, # 12 p. 925 - 940

全文：HTML全文

被引用次数: 15

摘要

Abstract New potent 5-HT 3 receptor antagonists have been designed from the naphthalimide moiety and a quinuclidine heterocycle and the structure-activity relationships are discussed here on the basis of the nature of the substituent on the aromatic system. ...