Convenient Formal Synthesis of (±)??Paroxetine

SP Chavan, DA Khobragade, AB Pathak…

文献索引：Chavan, Subhash P.; Khobragade, Dushant A.; Pathak, Ashok B.; Kalkote, Uttam R. Synthetic Communications, 2007 , vol. 37, # 18 p. 3143 - 3149

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被引用次数: 7

摘要

In connection with an ongoing program on the synthesis of biologically active compounds, we have recently developed a technically and economically viable protocol1 View all references for synthesis of the antidepressant drug venlafaxine 1. Our interest in development of practical routes for such molecules prompted us to undertake synthesis of another highly active antidepressant drug, paroxetine 2. ... The piperidine nucleus is ubiquitous in a wide variety of naturally ...