Appearance of Compound K, a Major Metabolite of Ginsenoside Rb1 by Intestinal Bacteria, in Rat Plasma after Oral Administration. Measurement of Compound K by …
Enzyme immunoassay (EIA) for the determination of compound K (CK), a major metabolite of ginsenoside Rb 1 (G-Rb 1) from Panax ginseng root by intestinal bacterial flora, was explored. Bovine serum albumin (BSA) was coupled to the C-26 position on the unsaturated side chain of CK. β-D-Galactosidase was introduced at the C-26 position of the saturated side chain. Antiserum, obtained by immunization of rabbits with CK-BSA conjugate, ...
