5-pyrrolidinylsulfonyl isatins as a potential tool for the molecular imaging of caspases in apoptosis

K Kopka, A Faust, P Keul, S Wagner…

文献索引：Journal of Medicinal Chemistry, , vol. 49, # 23 p. 6704 - 6715

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被引用次数: 73

摘要

... Journal of Medicinal Chemistry. ... 33 (The S1 pocket itself is composed of Arg, Gln, Arg, and Ser.) 34 Therefore, the 5-pyrrolidinylsulfonyl isatins should be potentially applicable in noninvasive nuclear medicine diagnosis with high clinical impact to differentiate between ...