The design and synthesis of water-soluble analogues of CB30865, a quinazolin-4-one-based antitumor agent

V Bavetsias, LA Skelton, F Yafai, F Mitchell…

文献索引：Journal of Medicinal Chemistry, , vol. 45, # 17 p. 3692 - 3702

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被引用次数: 36

摘要

... Journal of Medicinal Chemistry. ... Chemistry. This class of compounds was synthesized following the synthetic strategy that is outlined in Scheme 1. Thesynthesis starts with 3-chloro-4-methylaniline (1) which was converted ...