Methoxymethylation of Alcohols, Phenols, and Avermectin Aglycones Using MOM-2-pyridylsulfide

BF Marcune, S Karady, UH Dolling…

文献索引：Marcune; Karady; Dolling; Novak Journal of Organic Chemistry, 1999 , vol. 64, # 7 p. 2446 - 2449

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被引用次数: 22

摘要

Methoxymethyl-2-pyridylsulfide (MOM-ON) is an effective methoxymethylating reagent when used in conjunction with AgOTf, NaOAc, and THF. A wide range of MOM ethers are produced from corresponding phenols and alcohols, including tertiary and allylic alcohols, in good yields and under mild, neutral conditions. This method is also effective for the methoxymethylation of avermectin aglycones.