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Journal of Physical Organic Chemistry

Quinoline formation via a modified Combes reaction: examination of kinetics, substituent effects, and mechanistic pathways

JC Sloop

文献索引:Sloop, Joseph C. Journal of Physical Organic Chemistry, 2009 , vol. 22, # 2 p. 110 - 117

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被引用次数: 17

摘要

Abstract This is the first reported investigation of the Combes condensation employing 19F NMR spectroscopy to monitor intermediate consumption and product formation rates. The reaction was found to be first order in both the diketone and aniline. Product ...