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Synthesis of D-arabinohydroxamic acid and D-threonohydroxamic acid, potent inhibitors of D-xylose isomerases

A Gaudemer, C Fanet, F Gaudemer, L Salmon

文献索引:Gaudemer, Alain; Fanet, Catherine; Gaudemer, Francoise; Salmon, Laurent Tetrahedron Letters, 1996 ,  vol. 37,  # 13  p. 2237 - 2240

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被引用次数: 2

摘要

Two potent inhibitors of D-xylose isomerases: D-threonohydroxamic acid 2 and D- arabinohydroxamic acid 3 have been synthesized by conversion of D-arabinose to a protected derivative of D-arabinonic acid and introduction of the hydroxamate group by coupling with O-benzylhydroxylamine.