Two potent inhibitors of D-xylose isomerases: D-threonohydroxamic acid 2 and D- arabinohydroxamic acid 3 have been synthesized by conversion of D-arabinose to a protected derivative of D-arabinonic acid and introduction of the hydroxamate group by coupling with O-benzylhydroxylamine.
![(4S)-2,2-Dimethyl-5β-[(4R)-2,2-dimethyl-1,3-dioxolane-4β-yl]-1,3-dioxolane-4α-carbaldehyde Structure](https://image.chemsrc.com/caspic/479/13039-93-5.png)
