Synthesis

A Practical Synthesis of Indanofan via One-Pot Bromination of 3-Chloroethylbenzene

K Tanaka, A Hosokawa, K Yoshida

文献索引：Tanaka, Ken; Hosokawa, Akemi; Yoshida, Kenji Synthesis, 1999 , # 2 p. 249 - 253

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被引用次数: 2

摘要

Abstract: A practical synthesis of Indanofan (1), a potent herbicide discovered by Mitsubishi Chemical Co. Ltd., was achieved starting from commercially available 3-chloroethylbenzene (2). 3-Chloroα-bromostyrene (3), which was converted to 1-chloro-2-(3-chlorophenyl) prop-2- ene (5) in 2 steps, was synthesized via one-pot bromination of 2. 2-Ethylindane-1, 3-dione (6) was synthesized from ethyl butyrate and ethyl phthalate (11) using NaOEt. The ...