A series of 2-substituted indan-1, 3-dione derivatives, including alkyl (ClC-5), mono-and disubstituted phenyl, and other 2-aryl derivatives, were tested for hypolipidemic activity of CF, male mice at 20 mg/kg per day. These derivatives reduced both serum cholesterol and triglycerides after 16 days of administration intraperitoneally. 2-(4-Methoxyphenyl) indan-1, 3- dione was one of the more active compounds with 41% reduction of serum cholesterol ...
