Tetrahedron letters

Controlled mono and double Heck reactions in water catalyzed by an oxime-derived palladacycle

L Botella, C Nájera

文献索引：Botella, Luis; Najera, Carmen Tetrahedron Letters, 2004 , vol. 45, # 9 p. 1833 - 1836

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被引用次数: 100

摘要

The mono and β, β-diarylation of α, β-unsaturated carbonyl compounds with electron- deficient and electron-rich aromatic iodides in water is described. These reactions are catalyzed by the p-hydroxyacetophenone oxime-derived palladacycle by controlling the stoichiometry of the aryl iodide and the alkene as well as the loading of the palladium catalyst. This one-pot protocol is performed in refluxing water and (dicyclohexyl) ...