Tetrahedron letters

Tetraphosphine/palladium-catalyzed Heck reactions of aryl halides with disubstituted alkenes

I Kondolff, H Doucet, M Santelli

文献索引：Kondolff, Isabelle; Doucet, Henri; Santelli, Maurice Tetrahedron Letters, 2003 , vol. 44, # 46 p. 8487 - 8491

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被引用次数: 60

摘要

cis, cis, cis-1, 2, 3, 4-Tetrakis (diphenylphosphinomethyl) cyclopentane/[PdCl (C3H5)] 2 efficiently catalyses the Heck reaction of disubstituted alkenes such as methyl crotonate, ethyl cinnamate, methyl methacrylate or α-methylstyrene with a variety of aryl halides. In the presence of 1, 2-disubstituted alkenes the stereoselectivities of the reactions strongly depend on the substituents of the alkenes. Selectivities up to 97% in favor of E-isomers ...