t-Butyloxycarbonylamino acids and their use in peptide synthesis

GW Anderson, AC McGregor

文献索引：Anderson; McGregor Journal of the American Chemical Society, 1957 , vol. 79, p. 6180,6181

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被引用次数: 289

摘要

The introduction of the benzyloxycarbonyl (carbobenzoxy) group for the masking of amine groups' was a major contribution to peptide syntheses. Benzyloxycarbonyl derivatives are readily made and are usually crystalline, and the protecting group can be removed by several procedures. A number of analogous aryl-or alkyloxycarbonyl protecting groups have been investigated. 2 None of these provided the modification of the properties of the ...