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Structure—neuromuscular blocking activity relationships of ketophosphonium salts

R Houssin, JP Hénichart, M Foulon…

文献索引:Houssin; Henichart; Foulon; Baert Journal of Pharmaceutical Sciences, 1980 , vol. 69, # 8 p. 888 - 891

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被引用次数: 1

摘要

Abstract Three ketophosphonium salts containing a morpholino group were prepared and evaluated for their neuromuscular blocking effect. Solution and crystal conformations were studied. An attempt was made to explain, in structural terms, different activity levels in connection with the interatomic distances.