Nonacidic and highly chemoselective protection of the carbonyl function. 3-Methylbenzothiazolines as a base-and acid-resistant protected form for the carbonyl …

H Chikashita, S Komazawa, N Ishimoto…

文献索引：Chikashita, Hidenori; Komazawa, Shun-ichiro; Ishimoto, Nishiki; Inoue, Koji; Itoh, Kazuyoshi Bulletin of the Chemical Society of Japan, 1989 , vol. 62, # 4 p. 1215 - 1225

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被引用次数: 18

摘要

A simple and useful new type of protection method for carbonyl groups by conversion into 3- methylbenzothiazoline derivatives with o-(methylamino) benzenethiol was described. With this method, 3-methylbenzothiazolines were conveniently obtained in excellent yields from various aldehydes and ketones. This method allows efficient protection and deprotection under mild and neutral conditions and affords protection of the carbonyl group against ...