Synthesis

Design, synthesis and structure-odor correlation of novel spiro [4.5]-decan-2-ones

P Kraft, R Cadalbert

文献索引：Kraft, Philip; Cadalbert, Riccardo Synthesis, 2002 , # 15 p. 2243 - 2253

被引用次数: 6

摘要

Abstract Dehydration and Rupe rearrangement of 2-(3, 3-dimethylcyclohexyl) hex-3-yne-2, 5- diol (9) furnished as a 3% byproduct the intense vetiver-like smelling 4, 7, 7-trimethyl-1- methylenespiro [4.5] decan-2-one (11). Motivated by the commercial importance of vetiver oil and the lack of synthetic substitutes as well as the lack of insight into the structural requirements for vetiver odorants, an efficient synthetic route to vetiver-like smelling ...