Molecules

Comparative studies on conventional and microwave synthesis of some benzimidazole, benzothiazole and indole derivatives and testing on inhibition of …

O Algul, A Kaessler, Y Apcin, A Yilmaz, J Jose

文献索引：Algul, Oztekin; Kaessler, Andre; Apcin, Yagmur; Yilmaz, Akin; Jose, Joachim Molecules, 2008 , vol. 13, # 4 p. 736 - 748

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被引用次数: 54

摘要

Abstract: We have synthesized twelve 2-substituted benzimidazole, benzothiazole and indole derivatives using on both microwave irradiation and conventional heating methods. The microwave method was observed to be more beneficial as it provides an increase of yield from 3% to 113% and a 95 to 98% reduction in time. All compounds were tested by a stains-all assay at pH 7 and by a Morgan-Elson assay at pH 3.5 for hyaluronidase ...