Synlett

One-pot synthesis of functionalized benzimidazoles and 1H-pyrimidines via cascade reactions of o-aminoanilines or naphthalene-1, 8-diamine with alkynes and p- …

J She, Z Jiang, Y Wang

文献索引：She, Jin; Jiang, Zheng; Wang, Yanguang Synlett, 2009 , # 12 p. 2023 - 2027

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被引用次数: 31

摘要

Previously, we [¹¹] and other groups [¹²] developed the copper-catalyzed three-component reaction of sulfonyl azides with terminal alkynes and a number of nucleophiles, such as amines, alcohols or water. The reactions involve a copper-catalyzed azide-alkyne cycloaddtion (CuAAC) and the generation of a ketenimine intermediate. On the basis of these works, we investigated the copper(I) iodide catalyzed reaction of phenyl acetylene (1a) with p-tolylsulfonyl azide (2) ...