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Synthesis

Synthesis of biologically active seven-membered-ring heterocycles

…, ME Kavanagh, M Longworth, M Kassiou

文献索引:Reekie, Tristan A.; Kavanagh, Madeline E.; Longworth, Mitchell; Kassiou, Michael Synthesis (Germany), 2013 , vol. 45, # 23 p. 3211 - 3227

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被引用次数: 13

摘要

Abstract Seven-membered rings that contain one or more heteroatoms are interesting motifs for organic synthesis. In addition to their synthetic interest, they play an important role in industrial and pharmaceutical chemistry with generally increased central nervous system activity when flanked by aromatic rings. Herein we report a brief summary of some key methods of preparation for seven-membered-ring heterocycles and how they have been ...