The synthesis of 8-chloro-l-phenyl-3H-2-benzazepine analogues 6a-c and their dihydro derivatives 9a-c from the corresponding alkynes la-c is discussed. The bromination followed by dehydrobromination of 6a-c led to the formation of the corresponding 5-bromo-l-phenyl- 3H-2-benzazepines 14a-c which were useful synthetic intermediates in the synthesis of more complex 2-benzazepine derivatives. An example of the utility for the vinyl bromides ...
![[2-(3-aminoprop-1-ynyl)-5-chlorophenyl]-(2-fluorophenyl)methanone结构式](https://image.chemsrc.com/caspic/458/76049-63-3.png)
![[2-(3-aminoprop-1-ynyl)-5-chlorophenyl]-(2-chlorophenyl)methanone结构式](https://image.chemsrc.com/caspic/420/76049-64-4.png)
![[2-(3-aminoprop-1-ynyl)-5-chlorophenyl]-phenylmethanone结构式](https://image.chemsrc.com/caspic/034/76049-61-1.png)
