Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... An efficient one-pot-three-step method has been developed to assemble readily available aryl or heteroaryl halides, methyl trifluoropyruvate, and amines into biologically important α-hydroxy α-trifluoromethyl amides without isolation of any intermediates. ... Examples of biologically active ...