Synthesis and biological evaluation of novel nitrogen-and sulfur-containing hetero-1, 4-naphthoquinones as potent antifungal and antibacterial agents

…, O Komarovska-Porokhnyavets, V Novikov

文献索引：Ibis, Cemil; Tuyun, Amac Fatih; Ozsoy-Gunes, Zeliha; Bahar, Hakan; Stasevych, Maryna V.; Musyanovych, Rostyslav Ya.; Komarovska-Porokhnyavets, Olena; Novikov, Volodymyr European Journal of Medicinal Chemistry, 2011 , vol. 46, # 12 p. 5861 - 5867

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被引用次数: 25

摘要

1, 4-Naphthoquinones are unique reagents in organic synthesis and have been employed in several well known and recently developed areas of application. Furthermore, these 1, 4- naphthoquinones have demonstrated high reactivity in nucleophilic vinylic substitutions, in the preparation of sulfurated,(hetero) cyclic and several other transformations. This study describes the synthesis and biological evaluation of derivatives of monosulfurated ...