Synthesis and biological evaluation of novel nitrogen-and sulfur-containing hetero-1, 4-naphthoquinones as potent antifungal and antibacterial agents

…, O Komarovska-Porokhnyavets, V Novikov

Index: Ibis, Cemil; Tuyun, Amac Fatih; Ozsoy-Gunes, Zeliha; Bahar, Hakan; Stasevych, Maryna V.; Musyanovych, Rostyslav Ya.; Komarovska-Porokhnyavets, Olena; Novikov, Volodymyr European Journal of Medicinal Chemistry, 2011 , vol. 46, # 12 p. 5861 - 5867

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Citation Number: 25

Abstract

1, 4-Naphthoquinones are unique reagents in organic synthesis and have been employed in several well known and recently developed areas of application. Furthermore, these 1, 4- naphthoquinones have demonstrated high reactivity in nucleophilic vinylic substitutions, in the preparation of sulfurated,(hetero) cyclic and several other transformations. This study describes the synthesis and biological evaluation of derivatives of monosulfurated ...