Tetrahedron Letters

Addition of carbon nucleophiles to aldehyde tosylhydrazones of aromatic and heteroaromatic-compounds: total synthesis of piperine and its analogs†,‡

S Chandrasekhar, MV Reddy, KS Reddy, C Ramarao

文献索引：Chandrasekhar; Venkat Reddy; Srinivasa Reddy; Ramarao Tetrahedron Letters, 2000 , vol. 41, # 15 p. 2667 - 2670

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被引用次数: 20

摘要

Addition of carbon nucleophiles to aldehyde tosylhydrazones of aromatic and heteroaromatic compounds is reported. New observations have been made wherein alkylative reduction is observed in some cases whereas alkylative fragmentation is noticed in others. These findings are exploited in the synthesis of the useful alkaloid piperine and its analogs.