Phosphorus, Sulfur, and Silicon

Selenium analogues of anti-thyroid drugs

G Roy, G Mugesh

文献索引：Roy, Gouriprasanna; Mugesh, Govindasamy Phosphorus, Sulfur and Silicon and the Related Elements, 2008 , vol. 183, # 4 p. 908 - 923

全文：HTML全文

被引用次数: 5

摘要

The inhibition of lactoperoxidase (LPO)-catalyzed oxidation of ABTS by anti-thyroid drugs and related derivatives is described. The commonly used anti-thyroid agent methimazole (MMI) inhibits the LPO with an IC 50 value of 7.0±1.1 μ M which is much lower than that of