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Structure and synthesis of new anticoccidial antibiotics isolated from Streptomyces auranticolor

H Ikushima, S Takase, Y Kawai, Y Itoh…

文献索引:Ikushima; Takase; Kawai; et al. Agricultural and Biological Chemistry, 1983 , vol. 47, # 10 p. 2231 - 2235

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被引用次数: 9

摘要

The structures of two new anticoccidial antibiotics, WS-5995A and B, produced by Streptomyces auranticolor, were determined as I and II, respectively, on the basis of spectral and chemical evidence. WS-5995A (I), having 5 H-benzo [d] naphtho [2, 3-b] pyran as its mother skeleton, was synthesized by coupling the diazonium salt prepared from the anthranilic acid (IX) to 3-hydroxy juglone (VIII).