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… hydrocarbon-DNA interactions: a comparison of DNA influences on the reactivities of (.+-.)-trans-7, 8-dihydroxy-anti-9, 10-epoxy-7, 8, 9, 10-tetrahydrobenzo [a] pyrene …

S Urano, HL Price, SM Fetzer, AV Briedis…

文献索引:Urano, Shigeyuki; Price, Harry L.; Fetzer, Sharon M.; Briedis, Anita V.; Milliman, Ann; LeBreton, Pierre R. Journal of the American Chemical Society, 1991 , vol. 113, # 10 p. 3881 - 3893

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被引用次数: 18

摘要

Abstract: Time-resolved fluorescence and UV photoelectron measurements have been employed to examine the influence of calf thymus DNA on the reactivities of epoxides derived from benzo [a] pyrene (BP) and benz [a] anthracene (BA). By monitoring the increase in fluorescence intensity, which accompanies reaction at 23 OC, overall, pseudo- first-order rate constants have been measured for reactions of the highly carcinogenic bay ...