Tetrahedron letters

Three-step synthesis of 4-(2′-hydroxyethyl) azetidin-2-one and its substituted derivatives from 4-acetoxy-2-pyridones

C Kaneko, T Naito, A Saito

文献索引：Kaneko, Chikara; Naito, Toshihiko; Saito, Akemi Tetrahedron Letters, 1984 , vol. 25, # 15 p. 1591 - 1594

全文：HTML全文

被引用次数: 8

摘要

Abstract 4-(2'-Hydroxyethyl) azetidin-2-one, an important synthetic intermediate for carbapenem, and its substituted derivatives have been synthesized from 4-acetoxy-2- pyridones by photolysis, catalytic hydrogenation, followed by basic hydrolysis in the presence of sodium borohydride.